Current Team

Principal Investigator

Radhakrishnan (Krishna) Mahadevan

Professor of Chemical Engineering and Applied Chemistry

B.Tech., Indian Institute of Technology (IIT) - Madras, India
Ph.D., University of Delaware, USA

Email
krishna(DOT)mahadevan(AT)utoronto(DOT)ca

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Postdoctoral Fellows
Alessandra Biz

Research Associate

D.Sc., Universidade Federal do Parana - Curitiba, Brazil
M.Sc., Universidade Federal do Parana - Curitiba, Brazil
B.Eng., Universidade Federal do Parana - Curitiba, Brazil

Alessandra's work involves the engineering of yeast to produce adipic acid. She is particularly interested in using metabolic flux analyses to rewire yeast metabolism  to produce adipic acid, and in using CRISPR tools to engineer non-conventional yeasts.

Email
alessandra(DOT)biz(AT)utoronto(DOT)ca

Jinjin Chen

Research Associate

M.Sc., Chinese Academy of Sciences, China
D.Eng., Chinese Academy of Sciences, China

Jinjin primarily works on developing a gene editing method for Acidithiobacillus ferrooxidans. She also works on the metabolic engineering of Escherichia coli to produce bioproducts.

Email
jinjin(DOT)chen(AT)utoronto(DOT)ca

Yilan Liu

Research Associate

M.Sc., Chinese Academy of Sciences, China

D.Eng., Chinese Academy of Sciences, China

Yilan's research involves the metabolic engineering of Escherichia coli to produce bioproducts. She particularly focuses on using CRISPR, self-developed TRAGE tools and metabolic flux analyses to engineer E. coli to produce alkanes and alcohols.

Email
liu(DOT)yilan(AT)utoronto(DOT)ca

Marios Mejdani

Research Associate

B.Sc., University of Toronto
Ph.D., University of Toronto

Email
marios(DOT)mejdani(AT)mail(DOT)utoronto(DOT)ca

Graduate Students
 
Olivia Bulka

M.A.Sc. Student

B.Sc. (Hons), University of British Columbia

Olivia’s research involves the analysis and engineering of microbial communities to degrade chlorinated groundwater contaminants. Her research interests include synthetic biology and bioremediation.




Email
olivia(DOT)bulka(AT)mail(DOT)utoronto(DOT)ca

Ruhi Choudhary

Ph.D. Student

B.A.Sc., University of Toronto

Ruhi works on engineering probiotic strains for the production of therapeutic molecules to help treat diseases such as Crohn's Disease. Her research interests include synthetic biology, gut microbiome engineering, metabolic engineering and analytical chemistry.

Email ruhi(DOT)choudhary(AT)mail(DOT)utoronto(DOT)ca

Patrick Diep

Ph.D. Student

B.Sc., University of Waterloo

Patrick studies nickel binding proteins from soil and pathogenic bacteria to explore their potential applications as nickel capture/storage systems in biomining. His research interests include synthetic biology and environmental remediation.


Email
patrick(DOT)diep(AT)mail(DOT)utoronto(DOT)ca

Christian Euler

Ph.D. Student

B.A.Sc., University of Ottawa
B.Sc. (Hons), University of Ottawa

Christian works to understand regulatory mechanisms of metabolism at hierarchical and metabolic levels, and how these mechanisms interact. He uses protein engineering and optogenetic tools to create models of these control systems. His research interests include protein engineering, synthetic biology and modeling gene regulatory networks.

Email christian(DOT)euler(AT)mail(DOT)utoronto(DOT)ca

Mauricio Garcia Benitez

Ph.D. Student

B.Sc., UANL - Mexico
M.Sc., UNAM - Mexico City, Mexico

Mauricio works on developing a data-driven framework based on machine learning to integrate genome scale metabolic models with the design of genetic circuits for adipic acid production.



Email
mauricio(DOT)garciabenitez
(AT)mail(DOT)utoronto(DOT)ca

Dafni Giannari

Ph.D. Student

Diploma (M.S.), University of Patras - Greece

Dafni works on the mathematical modeling of metabolic networks.






Email
dafni(DOT)giannari(AT)mail(DOT)utoronto(DOT)ca

Sai Akhil Golla

Ph.D. Student

M.Tech., IIT Kharagpur - India

Akhil works on designing novel gene regulatory programs to control metabolism in cells.




Email
saiakhil(DOT)golla(AT)mail(DOT)utoronto(DOT)ca

Kiana Haddadi

Ph.D. Student

M.Sc., Ferdowsi University of Mashhad, Iran
B.Sc., Ferdowsi University of Mashhad, Iran

Kiana works on kinetic parameterization to better understand regulatory mechanisms in cells. She uses kinetic modeling to parameterize shifts in metabolic fluxes that assist cells to adapt to changes in environmental conditions.

Email
kiana(DOT)haddadi(AT)mail(DOT)utoronto(DOT)ca

Emma Harrison

M.A.Sc. Student

B.A.Sc., University of Ottawa B.Sc. (Hons), University of Ottawa

Emma works on identifying novel pathways for environmentally benign synthesis of biofuels and commodity chemicals.



Email
el(DOT)harrison(AT)mail(DOT)utoronto(DOT)ca

Alex Mulet Indrayanti

M.A.Sc. Student

B.Sc. (Hons), Carleton University

Alex works on the metabolic engineering of yeast to produce adipic acid. He also works on engineering Saccharomyces cerevisiae for effective fermentation of xylose.

 


Email
alex(DOT)mulet(AT)mail(DOT)utoronto(DOT)ca

Chester Pham

Ph.D. Student

B.S., University of Washington - Seattle, USA

Chester works on developing engineered biosensors to detect small molecules and metabolites for use in metabolic engineering.


 

Email chester(DOT)pham(AT)mail(DOT)utoronto(DOT)ca

Scott Proulx

M.A.Sc. Student

B.A.Sc., University of Ottawa
B.Sc. (Hons), University of Ottawa

Scott's research involves engineering Escherichia coli to produce commodity chemicals such as adipic acid. His research interests primarily involve metabolic engineering and dynamic control of synthetic pathways.

Email
scott(DOT)proulx(AT)mail(DOT)utoronto(DOT)ca

Kaushik Raj

Ph.D. Student

B.E. (Hons), BITS - Pilani, India

 

Kaushik works on developing and using computational models of metabolism and gene regulation to identify strategies and build genetic tools for dynamic metabolic pathway engineering. He has also worked on the engineering of baker's yeast (Saccharomyces cerevisiae) to produce adipic acid. His research interests include synthetic biology, data science, metabolic engineering and systems biology.

Email kaushik(DOT)venkatesan(AT)mail(DOT)utoronto(DOT)ca

Kavya Siddartha

Ph.D. Student

B.S., University of California - Berkeley, USA

 

Kavya primarily works on metabolic engineering of microbes for sustainable and scalable chemical production. Her focus has been designing modular biosynthetic pathways and modular host engineering. Her research interests include metabolic engineering, synthetic biology, and industrial biotechnology.



Email
kavya(DOT)siddartha(AT)utoronto(DOT)ca

Sheida Stephens

Ph.D. Student

B.A.Sc., University of Ottawa P.Eng.

Sheida works on developing metabolic models for purple bacteria and engineering them to function as chemical production platforms.

 







Email
sheida(DOT)stephens(AT)mail(DOT)utoronto(DOT)ca

Alexandre Tremblay

Ph.D. Student

B.Sc., Université du Québec à Trois-Rivières
M.Sc.., McGill University







Email alexandre(DOT)tremblay(AT)mail(DOT)utoronto(DOT)ca

Zhiqing(Paul) Xu

Ph.D. Student

B.A.Sc., University of Toronto
M.A.Sc., University of Toronto

Zhiqing (Paul) works on biochemical pathway prediction based on probabilistic and machine learning methods. He develops new algorithms to improve the efficiency of designing synthetic pathways for biological production of non-natural chemicals.

Email zhiqing(DOT)xu(AT)mail(DOT)utoronto(DOT)ca

Leo Zhu

Ph.D. Student

B.A.Sc., University of Toronto

Leo works on developing multi-scale models for gauging the effects of dietary interventions on hypercholesterolemia.



Email
leo(DOT)zhu(AT)mail(DOT)utoronto(DOT)ca

Undergraduate Students