Principal Investigator

Prof. Radhakrishnan Mahadevan

Canada Research Chair in Metabolic Systems Engineering (Tier 1, NSERC)

Professor, Chemical Engineering and Applied Chemistry, University of Toronto
(Cross Appointed with the Institute of Biomaterials and Biomedical Engineering - IBBME)

Associate Director of Computational Resources, BioZone

Associate Chair of Graduate Studies, Chemical Engineering and Applied Chemistry, University of Toronto

B.Tech., Indian Institute of Technology (IIT) - Madras, India (1997)
Ph.D., University of Delaware, USA (2002)

Email: krishna(DOT)mahadevan(AT)utoronto(DOT)ca

Prof. Mahadevan is a pioneer in the fields of systems biology, synthetic biology, and constraint-based models of metabolic networks. His research interests include systems analysis, engineering and control of biological processes, and genome-scale models of cellular processes. Applications of this work include optimization of bioremediation strategies, engineering for microbial fuel cells, and the designing cells to economically produce high-value chemical products. Using computational and experimental methods, Prof. Mahadevan was the first to model the unique metabolism of Geobacter sulfurreducens, an anaerobic metal-reducing bacterium with applications in bioremediation of toxic metals and bioelectricity generation. His computational expertise is critical to the development of organism-independent metabolic models based on the metagenome sequence data generated by researchers in BioZone.

Awards & Honors:
Biochemical Engineering Journal Young Investigator Award in 2017.
Syncrude Canada Innovation Award in 2014.
Alexander von Humboldt Fellowship in 2013.
University of Toronto FASE Research Leaders Award in 2013.
Society of Industrial Microbiology and Biotechnology Young Investigator Award in 2012.
Jay Bailey Young Investigator Best Paper Award from Metabolic Engineering Journal in 2010.
Early Researcher Award for Research Excellence in Ontario in 2008.
David W. Smith Jr. Award for Outstanding Publication in CAST Division of AIChE in 2006.
Departmental Teaching Fellowship at the University of Delaware in 2001.
University of Delaware Competitive Fellowship in 2000.
Hindustan Organic Chemicals Limited Scholarship in 1997.

Professional Memberships:
International Society of Microbial Ecology (2009-Present)
International Society of Computational Biology (2009-Present)
Canadian Society of Chemical Engineering (2009-Present)
Biophysical Society (2008-Present)
American Society of Microbiology (2004-Present)
American Institute of Chemical Engineers (2001-Present)

Professional Experience:
Associate Professor, Department of Chemical Engineering and Applied Chemistry, University of Toronto (2011 - 2016)
Assistant Professor, Department of Chemical Engineering and Applied Chemistry, University of Toronto (2006 - 2011)
Visiting Researcher, Department of Microbiology, University of Massachusetts, Amherst, USA (2006)
Research Scientist, Genomatica Inc., San Diego, USA (2003-2006)
Postdoctoral Fellow, Genomatica Inc., San Diego, USA (2002-2003)
Visiting Research Scholar, Department of Bioengineering, University of California, San Diego, USA (2002-2005)
Graduate Research Assistant, Department of Chemical Engineering, University of Delaware, Newark, USA (1997 - 2002)
Graduate Intern, DuPont, Wilmington, USA (2000)