About Us

The Lab for Metabolic Systems Engineering (LMSE) was established in the University of Toronto's Department of Chemical Engineering and Applied Chemistry under the leadership of Prof. Radhakrishnan Mahadevan in 2006. We primarily work on engineering the metabolism of microbes such as Escherichia coli and Saccharomyces cerevisiae to produce fuels, chemicals and therapeutic molecules. We also work on developing computational and experimental tools using metabolic models and synthetic biology respectively to achieve this goal. Read more about our projects here.